تحميل

Institut für Medizinische Virologie (Institute of Medical Virology)

2. أين يقع (يدرج العنوان والموقع الجغرافي كلاهما)؟
Institut für Medizinische Virologie, Medizinische Fakultät, Universität Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

N 47° 23' 52.08", E 8° 33' 01.92"

3. مسطح المساحات المختبرية تبعاً لمستوى الاحتواء
BL 3 , م2 25.00
Of note, the Institute of Medical Virology holds a BSL4 license for diagnostic purposes only, as follows: “Inactivation or extraction of environmental samples or samples with potentially highly pathogenic viruses for diagnostic purposes”.
إجمالي مساحة المختبر (م2)
25

4. الهيكل التنظيمي لكل مرفق

'8' صف بإيجاز سياسة المرفق في مجال النشر

Publication in open literature.

'9' تقدم قائمة بالبحوث والتقارير المتاحة للجمهور من بين ما نُشر من الأعمال خلال الشهور ال‍ 12 الأخيرة. (تدرج أسماء المؤلفين وعناوين الدراسات، والمراجع الكاملة).

Gabrielaite, Migle; Bennedbæk, Marc; Zucco, Adrian G; Ekenberg, Christina; Murray, Daniel D; Kan, Virginia L; Touloumi, Giota; Vandekerckhove, Linos; Turner, Dan; Neaton, James; Lane, H Clifford; Safo, Sandra; Arenas-Pinto, Alejandro; Polizzotto, Mark N; Günthard, Huldrych F; Lundgren, Jens D; Marvig, Rasmus L  (2021). Human immunotypes impose selection on viral genotypes through viral epitope specificity. Journal of Infectious Diseases, 224(12):2053-2063.

Schoepf, Isabella C; Thorball, Christian W; Ledergerber, Bruno; Kootstra, Neeltje A; Reiss, Peter; Raffenberg, Marieke; Engel, Tanja; Braun, Dominique L; Hasse, Barbara; Thurnheer, Christine; Marzolini, Catia; Seneghini, Marco; Bernasconi, Enos; Cavassini, Matthias; Buvelot, Hélène; Arribas, José R; Kouyos, Roger D; Fellay, Jacques; Günthard, Huldrych F; Tarr, Philip E; Swiss HIV Cohort Study  (2021). Telomere Length Declines In Persons Living With HIV Before Antiretroviral Therapy Start But Not After Viral Suppression: A Longitudinal Study Over >17 Years. Journal of Infectious Diseases:Epub ahead of print.

Abela, Irene A; Pasin, Chloé; Schwarzmüller, Magdalena; Epp, Selina; Sickmann, Michèle E; Schanz, Merle M; Rusert, Peter; Weber, Jacqueline; Schmutz, Stefan; Audigé, Annette; Maliqi, Liridona; Hunziker, Annika; Hesselman, Maria C; Niklaus, Cyrille R; Gottschalk, Jochen; Schindler, Eméry; Wepf, Alexander; Karrer, Urs; Wolfensberger, Aline; Rampini, Silvana K; Meyer Sauteur, Patrick M; Berger, Christoph; Huber, Michael; Böni, Jürg; Braun, Dominique L; Marconato, Maddalena; Manz, Markus G; Frey, Beat M; Günthard, Huldrych F; Kouyos, Roger D; et al  (2021). Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity. Nature Communications, 12:6703.

Balakrishna, Suraj; Wolfensberger, Aline; Kachalov, Viacheslav; Roth, Jan A; Kusejko, Katharina; Scherrer, Alexandra U; Furrer, Hansjakob; Hauser, Christoph; Calmy, Alexandra; Cavassini, Matthias; Schmid, Patrick; Bernasconi, Enos; Battegay, Manuel; Günthard, Huldrych F; Kouyos, Roger D  (2021). Decreasing incidence and determinants of Bacterial Pneumonia in people with HIV: The Swiss HIV Cohort Study. Journal of Infectious Diseases:Epub ahead of print.

Friedrich, Nikolas; Stiegeler, Emanuel; Glögl, Matthias; Lemmin, Thomas; Hansen, Simon; Kadelka, Claus; Wu, Yufan; Ernst, Patrick; Maliqi, Liridona; Foulkes, Caio; Morin, Mylène; Eroglu, Mustafa; Liechti, Thomas; Ivan, Branislav; Reinberg, Thomas; Schaefer, Jonas V; Karakus, Umut; Ursprung, Stephan; Mann, Axel; Rusert, Peter; Kouyos, Roger D; Robinson, John A; Günthard, Huldrych F; Plückthun, Andreas; Trkola, Alexandra  (2021). Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nature Communications, 12:6705.

Ulyte, Agne; Radtke, Thomas; Abela, Irene A; Haile, Sarah R; Ammann, Priska; Berger, Christoph; Trkola, Alexandra; Fehr, Jan; Puhan, Milo A; Kriemler, Susi  (2021). Evolution of SARS-CoV-2 seroprevalence and clusters in school children from June 2020 to April 2021: prospective cohort study Ciao Corona. Swiss Medical Weekly, 151:w30092.

Schoepf, Isabella C; Thorball, Christian W; Ledergerber, Bruno; Engel, Tanja; Raffenberg, Marieke; Kootstra, Neeltje A; Reiss, Peter; Hasse, Barbara; Marzolini, Catia; Thurnheer, Christine; Seneghini, Marco; Bernasconi, Enos; Cavassini, Matthias; Buvelot, Hélène; Kouyos, Roger; Günthard, Huldrych F; Fellay, Jacques; Tarr, Philip E; Swiss HIV Cohort Study  (2021). Coronary Artery Disease-associated and Longevity-associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living with HIV: The Swiss HIV Cohort Study. Clinical Infectious Diseases, 73(9):1597-1604.

Courlet, Perrine; Barbieux, Charlotte; Sculier, Delphine; Wandeler, Gilles; Stoeckle, Marcel; Bernasconi, Enos; Braun, Dominique; Vernazza, Pietro; Cavassini, Matthias; Marinosci, Annalisa; Smit, Mikaela; Günthard, Huldrych F; Schmid, Patrick; Limacher, Andreas; Guidi, Monia; Alves Saldanha, Susana; Decosterd, Laurent Arthur; Calmy, Alexandra  (2021). Pharmacokinetic parameters and weight change in HIV patients newly switched to dolutegravir-based regimens in SIMPL'HIV clinical trial. British Journal of Clinical Pharmacology, 87(11):4455-4460.

Stertz, Silke; Hale, Benjamin G  (2021). Interferon system deficiencies exacerbating severe pandemic virus infections. Trends in Microbiology, 29(11):973-982.

Balakrishna, Suraj; Salazar-Vizcaya, Luisa; Schmidt, Axel J; Kachalov, Viacheslav; Kusejko, Katharina; Thurnheer, Maria Christine; Roth, Jan A; Nicca, Dunja; Cavassini, Matthias; Battegay, Manuel; Schmid, Patrick; Bernasconi, Enos; Günthard, Huldrych F; Rauch, Andri; Kouyos, Roger D; Swiss HIV Cohort Study  (2021). Assessing the drivers of syphilis among men who have sex with men in Switzerland reveals a key impact of screening frequency: A modelling study. PLoS Computational Biology, 17(10):e1009529.

Riou, Julien; Dupont, Carole; Bertagnolio, Silvia; Gupta, Ravindra K; Kouyos, Roger D; Egger, Matthias; Althaus, Christian L  (2021). Correction to: Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study. BMC Infectious Diseases, 21:1098.

Speich, Benjamin; Chammartin, Frédérique; Smith, Daniel; Stoeckle, Marcel P; Amico, Patrizia; Eichenberger, Anna L; Hasse, Barbara; Schuurmans, Macé M; Müller, Thomas; Tamm, Michael; Dickenmann, Michael; Abela, Irene A; Trkola, Alexandra; Hirsch, Hans H; Manuel, Oriol; Cavassini, Matthias; Hemkens, Lars G; Briel, Matthias; Mueller, Nicolas J; Rauch, Andri; Günthard, Huldrych F; Koller, Michael T; Bucher, Heiner C; Kusejko, Katharina  (2021). A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®. Trials, 22:724.

Roth, Jan A; Radevski, Gorjan; Marzolini, Catia; Rauch, Andri; Günthard, Huldrych F; Kouyos, Roger D; Fux, Christoph A; Scherrer, Alexandra U; Calmy, Alexandra; Cavassini, Matthias; Kahlert, Christian R; Bernasconi, Enos; Bogojeska, Jasmina; Battegay, Manuel  (2021). Cohort-derived machine learning models for individual prediction of chronic kidney disease in people living with HIV: a prospective multicentre cohort study. Journal of Infectious Diseases, 224(7):1198-1208.

Riou, Julien; Dupont, Carole; Bertagnolio, Silvia; Gupta, Ravindra K; Kouyos, Roger D; Egger, Matthias; Althaus, Christian L  (2021). Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study. BMC Infectious Diseases, 21:1042.

Braun, Dominique L; Hampel, Benjamin; Ledergerber, Bruno; Grube, Christina; Nguyen, Huyen; Künzler-Heule, Patrizia; Shah, Cyril; Salazar-Vizcaya, Luisa; Conen, Anna; Flepp, Markus; Stöckle, Marcel; Béguelin, Charles; Schmid, Patrick; Rougemont, Mathieu; Delaloye, Julie; Bernasconi, Enos; Nicca, Dunja; Böni, Jürg; Rauch, Andri; Kouyos, Roger D; Günthard, Huldrych F; Fehr, Jan S  (2021). A treatment as prevention trial to eliminate hepatitis C among men who have sex with men living with HIV in the Swiss HIV Cohort Study. Clinical Infectious Diseases, 73(7):e2194-e2202.

Deutschmann, Elisabeth; Bucher, Heiner C; Jaeckel, Steffen; Gibbons, Sara; McAllister, Katie; Scherrer, Alexandra U; Braun, Dominique L; Cavassini, Matthias; Hachfeld, Anna; Calmy, Alexandra; Battegay, Manuel; Cipriani, Michela; Elzi, Luigia; Young, James; Lopez-Centeno, Beatriz; Berenguer, Juan; Khoo, Saye; Moffa, Giusi; Marzolini, Catia; Swiss HIV Cohort Study  (2021). Prevalence of potential drug-drug interactions in patients of the Swiss HIV Cohort Study in the era of HIV integrase inhibitors. Clinical Infectious Diseases, 73(7):e2145-e2152.

Engel, Tanja; Raffenberg, Marieke; Schoepf, Isabella C; Kootstra, Neeltje A; Reiss, Peter; Thorball, Christian W; Hasse, Barbara; Hirzel, Cédric; Wissel, Kerstin; Roth, Jan A; Bernasconi, Enos; Darling, Katharine E A; Calmy, Alexandra; Fellay, Jacques; Kouyos, Roger D; Günthard, Huldrych F; Ledergerber, Bruno; Tarr, Philip E  (2021). Telomere Length, Traditional Risk Factors, HIV-related Factors and Coronary Artery Disease Events in Swiss Persons Living with HIV. Clinical Infectious Diseases, 73(7):e2070-e2076.

Greenberg, Lauren; Ryom, Lene; Neesgaard, Bastian; Wandeler, Gilles; Staub, Therese; Gisinger, Martin; Skoll, Michael; Günthard, Huldrych F; et al  (2021). Clinical outcomes of two-drug regimens vs. three-drug regimens in antiretroviral treatment-experienced people living with HIV. Clinical Infectious Diseases, 73(7):e2323-e2333.

Pyngottu, Ashima; Scherrer, Alexandra U; Kouyos, Roger; Huber, Michael; Hirsch, Hans; Perreau, Matthieu; Yerly, Sabine; Calmy, Alexandra; Cavassini, Matthias; Stöckle, Marcel; Furrer, Hansjakob; Vernazza, Pietro; Bernasconi, Enos; Günthard, Huldrych F; Swiss HIV Cohort Study  (2021). Predictors of virological failure and time to viral suppression of first line integrase inhibitor based antiretroviral treatment. Clinical Infectious Diseases, 73(7):e2134-e2141.

Wolters, Femke; Grünberg, Maria; Huber, Michael; Kessler, Harald H; Prüller, Florian; Saleh, Lanja; Fébreau, Christine; Rahamat-Langendoen, Janette; Thibault, Vincent; Melchers, Willem J G  (2021). European multicenter evaluation of Xpert® Xpress SARS-CoV-2/Flu/RSV test. Journal of Medical Virology, 93(10):5798-5804.

Mazel-Sanchez, Beryl; Iwaszkiewicz, Justyna; Bonifacio, Joao P P; Silva, Filo; Niu, Chengyue; Strohmeier, Shirin; Eletto, Davide; Krammer, Florian; Tan, Gene; Zoete, Vincent; Hale, Benjamin G; Schmolke, Mirco  (2021). Influenza A viruses balance ER stress with host protein synthesis shutoff. Proceedings of the National Academy of Sciences of the United States of America, 118(36):e2024681118.

Posada-Céspedes, Susana; Van Zyl, Gert; Montazeri, Hesam; Kuipers, Jack; Rhee, Soo-Yon; Kouyos, Roger; Günthard, Huldrych F; Beerenwinkel, Niko  (2021). Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C. PLoS Computational Biology, 17(9):e1008363.

Moldt, Brian; Parvangada, Aiyappa; Martin, Ross; Pace, Craig; Balakrishnan, Mini; Thomsen, Nathan D; E Collins, Sean; Kuster, Herbert; Braun, Dominique L; Günthard, Huldrych F; Geleziunas, Romas; Callebaut, Christian  (2021). Evaluation of Broadly Neutralizing Antibody Sensitivity by Genotyping and Phenotyping for Qualifying Participants to HIV Clinical Trials. Journal of Acquired Immune Deficiency Syndromes, 88(1):61-69.

Kusejko, Katharina; Neofytos, Dionysios; Hirsch, Hans H; Meylan, Pascal; Boggian, Katia; Hirzel, Cedric; Garzoni, Christian; Kouyos, Roger D; Mueller, Nicolas J; Schreiber, Peter W; Swiss Transplant Cohort Study  (2021). Differences Between Infectious Disease Events in First Liver Transplant Versus Retransplantation in the Swiss Transplant Cohort Study. Liver Transplantation, 27(9):1283-1290.

Steiner, Fiona; Schmutz, Stefan; Gosert, Rainer; Huder, Jon B; Redli, Patrick M; Capaul, Riccarda; Hirsch, Hans H; Böni, Jürg; Zbinden, Andrea  (2021). Usefulness of the GenMark ePlex RPP assay for the detection of respiratory viruses compared to the FTD21 multiplex RT-PCR. Diagnostic Microbiology and Infectious Disease, 101:115424.

Audigé, Annette; Böni, Jürg; Schreiber, Peter W; Scheier, Thomas; Buonomano, Roberto; Rudiger, Alain; Braun, Dominique L; Eich, Gerhard; Keller, Dagmar I; Hasse, Barbara; Berger, Christoph; Günthard, Huldrych F; Manrique, Amapola; Trkola, Alexandra; Huber, Michael  (2021). Reduced Relative Sensitivity of the Elecsys SARS-CoV-2 Antigen Assay in Saliva Compared to Nasopharyngeal Swabs. Microorganisms, 9(8):1700.

Thorball, Christian W; Oudot-Mellakh, Tiphaine; Ehsan, Nava; Hammer, Christian; Santoni, Federico A; Niay, Jonathan; Costagliola, Dominique; Goujard, Cécile; Meyer, Laurence; Wang, Sophia S; Hussain, Shehnaz K; Theodorou, Ioannis; Cavassini, Matthias; Rauch, Andri; Battegay, Manuel; Hoffmann, Matthias; Schmid, Patrick; Bernasconi, Enos; Günthard, Huldrych F; Mohammadi, Pejman; McLaren, Paul J; Rabkin, Charles S; Besson, Caroline; Fellay, Jacques  (2021). Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma. Haematologica, 106(8):2233-2241.

Vavassori, Stefano; Chou, Janet; Faletti, Laura Eva; Haunerdinger, Veronika; Opitz, Lennart; Joset, Pascal; Fraser, Christopher J; Prader, Seraina; Gao, Xianfei; Schuch, Luise A; Wagner, Matias; Hoefele, Julia; Maccari, Maria Elena; Zhu, Ying; Elakis, George; Gabbett, Michael T; Forstner, Maria; Omran, Heymut; Kaiser, Thomas; Kessler, Christina; Olbrich, Heike; Frosk, Patrick; Almutairi, Abduarahman; Platt, Craig D; Elkins, Megan; Weeks, Sabrina; Rubin, Tamar; Planas, Raquel; Marchetti, Tommaso; Koovely, Danil; Brotschi, Barbara; Laube, Guido; Güngör, Tayfun; Kottke, Raimund; Weber, Achim; Griese, Matthias; Pachlopnik Schmid, Jana; et al  (2021). Multisystem Inflammation and Susceptibility to Viral infections in Human ZNFX1 Deficiency. Journal of Allergy and Clinical Immunology, 148(2):381-393.

Palika, Archana; Armanious, Antonius; Rahimi, Akram; Medaglia, Chiara; Gasbarri, Matteo; Handschin, Stephan; Rossi, Antonella; Pohl, Marie O; Busnadiego, Idoia; Gübeli, Christian; Anjanappa, Ravi B; Bolisetty, Sreenath; Peydayesh, Mohammad; Stertz, Silke; Hale, Benjamin G; Tapparel, Caroline; Stellacci, Francesco; Mezzenga, Raffaele  (2021). An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles. Nature Nanotechnology, 16(8):918-925.

Ulyte, Agne; Radtke, Thomas; Abela, Irene Alma; Haile, Sarah R; Blankenberger, Jacob; Jung, Ruedi; Capelli, Celine; Berger, Christoph; Frei, Anja; Huber, Michael; Schanz, Merle; Schwarzmueller, Magdalena; Trkola, Alexandra; Fehr, Jan; Puhan, Milo Alan; Kriemler, Susi  (2021). Variation in SARS-CoV-2 seroprevalence across districts, schools and classes: baseline measurements from a cohort of primary and secondary school children in Switzerland. BMJ Open, 11(7):e047483.

Nguyen, Huyen; Hampel, Benjamin; Nuñez, David Garcia; Battegay, Manuel; Hachfeld, Anna; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Vernazza, Pietro; Fellay, Jacques; Rudolph, Hannes; Huber, Michael; Leuzinger, Karoline; Perreau, Matthieu; Scherrer, Alexandra; Ramette, Alban Nicolas; Yerly, Sabine; Günthard, Huldrych F; Kouyos, Roger D; Kusejko, Katharina; Swiss HIV Cohort Study  (2021). Identifying and Characterizing Trans women in the Swiss HIV Cohort Study as an Epidemiologically Distinct Risk Group. Clinical Infectious Diseases:Epub ahead of print.

Hirschi, Stephan; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios  (2021). Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin. Nature Communications, 12:4107.

Pohl, Marie O; Busnadiego, Idoia; Marrafino, Francesco; Wiedmer, Lars; Hunziker, Annika; Fernbach, Sonja; Glas, Irina; Moroz-Omori, Elena V; Hale, Benjamin G; Caflisch, Amedeo; Stertz, Silke  (2021). Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir. Journal of General Virology, 102(7):001625.

Achermann, Yvonne; Kusejko, Katharina; Auñón, Álvaro; Clauss, Martin; Corvec, Stéphane; Esteban, Jaime; Fernandez-Sampedro, Marta; Ferrari, Matteo Carlo; Gassmann, Natalie; Jent, Philipp; Jost, Bernhard; Kouyos, Roger D; Kramer, Tobias Siegfried; Lora-Tamayo, Jaime; Morand, Philippe C; Benito, Natividad; Pablo-Marcos, Daniel; Patel, Robin; Scanferla, Giulia; Sendi, Parham; Slama, Dorsaf; Stadelmann, Vincent A; Strahm, Carol; Thurnheer, Christine; Trebše, Rihard; Uckay, Ilker; Vijayvargiya, Prakhar; Waldmann, Isabelle; Wouthuyzen-Bakker, Marjan  (2021). The impact of surgical strategy and rifampin on treatment outcome in Cutibacterium periprosthetic joint infections. Clinical Infectious Diseases, 72(12):e1064-e1073.

Bachmann, Nadine; Kusejko, Katharina; Nguyen, Huyen; Chaudron, Sandra E; Kadelka, Claus; Turk, Teja; Böni, Jürg; Perreau, Matthieu; Klimkait, Thomas; Yerly, Sabine; Battegay, Manuel; Rauch, Andri; Ramette, Alban; Vernazza, Pietro; Bernasconi, Enos; Cavassini, Matthias; Günthard, Huldrych F; Kouyos, Roger D; Swiss HIV Cohort Study  (2021). Phylogenetic cluster analysis identifies virological and behavioral drivers of HIV transmission in MSM. Clinical Infectious Diseases, 72(12):2175-2183.

Deng, Yun; Chatterjee, Bithi; Zens, Kyra; Zdimerova, Hana; Müller, Anne; Schuhmachers, Patrick; Ligeon, Laure-Anne; Bongiovanni, Antonino; Capaul, Riccarda; Zbinden, Andrea; Holler, Angelika; Stauss, Hans; Hammerschmidt, Wolfgang; Münz, Christian  (2021). CD27 is required for protective lytic EBV antigen-specific CD8+ T-cell expansion. Blood, 137(23):3225-3236.

Nguyen, Huyen; Thorball, Christian Wandell; Fellay, Jacques; Böni, Jürg; Yerly, Sabine; Perreau, Matthieu; Hirsch, Hans H; Kusejko, Katharina; Thurnheer, Maria Christine; Battegay, Manuel; Cavassini, Matthias; Kahlert, Christian R; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger D; Swiss HIV Cohort Study  (2021). Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link. eLife, 10:e67388.

Echavarría-Consuegra, Liliana; Cook, Georgia M; Busnadiego, Idoia; Lefèvre, Charlotte; Keep, Sarah; Brown, Katherine; Doyle, Nicole; Dowgier, Giulia; Franaszek, Krzysztof; Moore, Nathan A; Siddell, Stuart G; Bickerton, Erica; Hale, Benjamin G; Firth, Andrew E; Brierley, Ian; Irigoyen, Nerea  (2021). Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection. PLoS Pathogens, 17(6):e1009644.

Sempere Borau, Milagros; Stertz, Silke  (2021). Entry of influenza A virus into host cells - recent progress and remaining challenges. Current Opinion in Virology, 48:23-29.

Kok, Yik Lim; Vongrad, Valentina; Chaudron, Sandra E; Shilaih, Mohaned; Leemann, Christine; Neumann, Kathrin; Kusejko, Katharina; Di Giallonardo, Francesca; Kuster, Herbert; Braun, Dominique L; Kouyos, Roger D; Günthard, Huldrych F; Metzner, Karin J  (2021). HIV-1 integration sites in CD4+ T cells during primary, chronic, and late presentation of HIV-1 infection. Journal of clinical investigation insight, 6(9):e143940.

Tamò, Raphaël; Turk, Teja; Böni, Jürg; Kouyos, Roger D; Schmutz, Stefan; Huber, Michael; Shah, Cyril; Bischoff-Ferrari, Heike A; Distler, Oliver; Battegay, Edouard; Giovanoli, Pietro; Guckenberger, Matthias; Kohler, Malcolm; Müller, Rouven; Petry, Heidi; Ruschitzka, Frank; McGeer, Allison; Sax, Hugo; Weber, Rainer; Trkola, Alexandra; Kuster, Stefan P  (2021). Secondary attack rates from asymptomatic and symptomatic influenza virus shedders in hospitals: Results from the TransFLUas influenza transmission study. Infection Control and Hospital Epidemiology:Epub ahead of print.

de Vries, Jutte J C; Brown, Julianne R; Couto, Natacha; Beer, Martin; Le Mercier, Philippe; Sidorov, Igor; Papa, Anna; Fischer, Nicole; Oude Munnink, Bas B; Rodriquez, Christophe; Zaheri, Maryam; Sayiner, Arzu; Hönemann, Mario; Pérez-Cataluña, Alba; Carbo, Ellen C; Bachofen, Claudia; Kubacki, Jakub; et al  (2021). Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting. Journal of Clinical Virology, 138:104812.

Hunziker, Annika. Phosphorylation Events in Early Steps of Human and Avian Influenza A Virus Infection. 2021, University of Zurich, Medizinische Fakultät.

Reichmuth, M L; Chaudron, S E; Bachmann, N; Nguyen, H; Böni, J; Metzner, K J; Perreau, M; Klimkait, T; Yerly, S; Hirsch, H H; Hauser, C; Ramette, A; Vernazza, P; Cavassini, M; Bernasconi, E; Günthard, H F; Kusejko, K; Kouyos, R D; Swiss HIV Cohort Study  (2021). Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV-1 transmission. HIV Medicine, 22(5):346-359.

Glass, Tracy R; Günthard, Huldrych; Calmy, Alexandra; Bernasconi, Enos; Scherrer, Alexandra U; Battegay, Manuel; Steffen, Ana; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Cavassini, Matthias; Furrer, Hansjakob; Swiss HIV Cohort Study  (2021). The role of HIV asymptomatic status when starting ART on adherence and treatment outcomes and implications for test and treat: the Swiss HIV Cohort Study. Clinical Infectious Diseases, 72(8):1413-1421.

Caillat, Christophe; Guilligay, Delphine; Torralba, Johana; Friedrich, Nikolas; Nieva, Jose L; Trkola, Alexandra; Chipot, Christophe J; Dehez, François L; Weissenhorn, Winfried  (2021). Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies. eLife, 10:e65005.

Muller, Christina K S; Spagnuolo, Julian; Audigé, Annette; Chancellor, Andrew; Russenberger, Doris; Scherrer, Alexandra U; Hoffmann, Matthias; Kouyos, Roger; Battegay, Manuel; De Libero, Gennaro; Speck, Roberto F; Swiss HIV Cohort Study  (2021). Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin's lymphoma. Infectious Agents and Cancer, 16:24.

Künzler-Heule, Patrizia; Fierz, Katharina; Schmidt, Axel Jeremias; Rasi, Manuela; Bogdanovic, Jasmina; Kocher, Agnes; Engberg, Sandra; Battegay, Manuel; Nöstlinger, Christiana; Lehner, Andreas; Kouyos, Roger; Schmid, Patrick; Braun, Dominique Laurent; Fehr, Jan; Nicca, Dunja  (2021). Response to a sexual risk reduction intervention provided in combination with hepatitis C treatment by HIV/HCV co-infected men who have sex with men: a reflexive thematic analysis. BMC Infectious Diseases, 21:319.

Raffenberg, Marieke; Engel, Tanja; Schoepf, Isabella C; Kootstra, Neeltje A; Reiss, Peter; Braun, Dominique L; Thorball, Christian W; Fellay, Jacques; Kouyos, Roger D; Ledergerber, Bruno; Günthard, Huldrych F; Tarr, Philip E; Zurich Primary HIV Infection Study; Swiss HIV Cohort Study  (2021). Impact of Delaying Antiretroviral Treatment during Primary HIV Infection on Telomere Length. Journal of Infectious Diseases:Epub ahead of print.

Goncalves Cabecinhas, Ana Rita; Roloff, Tim; Stange, Madlen; Bertelli, Claire; Huber, Michael; Ramette, Alban; Chen, Chaoran; Nadeau, Sarah; Gerth, Yannick; Yerly, Sabine; Opota, Onya; Pillonel, Trestan; Schuster, Tobias; Metzger, Cesar M J A; Sieber, Jonas; Bel, Michael; Wohlwend, Nadia; Baumann, Christian; Koch, Michel C; Bittel, Pascal; Leuzinger, Karoline; Brunner, Myrta; Suter-Riniker, Franziska; Berlinger, Livia; Søgaard, Kirstine K; Beckmann, Christiane; Noppen, Christoph; Redondo, Maurice; Steffen, Ingrid; Seth-Smith, Helena M B; et al  (2021). SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021—Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing. Microorganisms, 9(4):677.

Werner, Jana; Reichen, Ina; Huber, Michael; Abela, Irene A; Weller, Michael; Jelcic, Ilijas  (2021). Subacute cerebellar ataxia following respiratory symptoms of COVID-19: a case report. BMC Infectious Diseases, 21:298.

Lork, Marie; Lieber, Gauthier; Hale, Benjamin G  (2021). Proteomic Approaches to Dissect Host SUMOylation during Innate Antiviral Immune Responses. Viruses, 13(3):528.

Huber, Michael; Schreiber, Peter Werner; Scheier, Thomas; Audigé, Annette; Buonomano, Roberto; Rudiger, Alain; Braun, Dominique L; Eich, Gerhard; Keller, Dagmar I; Hasse, Barbara; Böni, Jürg; Berger, Christoph; Günthard, Huldrych F; Manrique, Amapola; Trkola, Alexandra  (2021). High Efficacy of Saliva in Detecting SARS-CoV-2 by RT-PCR in Adults and Children. Microorganisms, 9(3):642.

Ulyte, Agne; Radtke, Thomas; Abela, Irene A; Haile, Sarah R; Berger, Christoph; Huber, Michael; Schanz, Merle; Schwarzmueller, Magdalena; Trkola, Alexandra; Fehr, Jan; Puhan, Milo A; Kriemler, Susi  (2021). Clustering and longitudinal change in SARS-CoV-2 seroprevalence in school children in the canton of Zurich, Switzerland: prospective cohort study of 55 schools. BMJ : British medical journal, 372:n616.

Scheier, Thomas; Shah, Cyril; Huber, Michael; Sax, Hugo; Hasse, Barbara; Günthard, Huldrych F; Trkola, Alexandra; Schreiber, Peter W  (2021). Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center. Antimicrobial Resistance and Infection Control, 10:51.

Rindler, Audrey E; Kuster, Herbert; Neumann, Kathrin; Leemann, Christine; Braun, Dominique L; Metzner, Karin J; Günthard, Huldrych F  (2021). A Novel High Throughput, Parallel Infection Assay for Determining the Replication Capacities of 346 Primary HIV-1 Isolates of the Zurich Primary HIV-1 Infection Study in Primary Cells. Viruses, 13(3):404.

Kuster, Stefan P; Böni, Jürg; Kouyos, Roger D; Huber, Michael; Schmutz, Stefan; Shah, Cyril; Bischoff-Ferrari, Heike A; Distler, Oliver; Battegay, Edouard; Giovanoli, Pietro; Guckenberger, Matthias; Kohler, Malcolm; Müller, Rouven; Petry, Heidi; Ruschitzka, Frank; McGeer, Allison; Coleman, Brenda L; Sax, Hugo; Weber, Rainer; Trkola, Alexandra  (2021). Absenteeism and presenteeism in healthcare workers due to respiratory illness. Infection Control and Hospital Epidemiology, 42(3):268-273.

Pohl, Marie O; Busnadiego, Idoia; Kufner, Verena; Glas, Irina; Karakus, Umut; Schmutz, Stefan; Zaheri, Maryam; Abela, Irene; Trkola, Alexandra; Huber, Michael; Stertz, Silke; Hale, Benjamin G  (2021). SARS-CoV-2 variants reveal features critical for replication in primary human cells. PLoS Biology, 19(3):e3001006.

Hovaguimian, Frédérique; Günthard, Huldrych F; Hauser, Christoph; Conen, Anna; Bernasconi, Enos; Calmy, Alexandra; Cavassini, Matthias; Seneghini, Marco; Marzel, Alex; Heinrich, Henriette; Scherrer, Alexandra; Riou, Julien; Spoerri, Adrian; Schmidlin, Kurt; Balakrishna, Suraj; Braun, Dominique L; Rampini, Silvana K; Fehr, Jan S; Kouyos, Roger D; Swiss HIV Cohort Study  (2021). Data linkage to evaluate the long-term risk of HIV infection in individuals seeking post-exposure prophylaxis. Nature Communications, 12:1219.

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Kachalov, Viacheslav N; Nguyen, Huyen; Balakrishna, Suraj; Salazar-Vizcaya, Luisa; Sommerstein, Rami; Kuster, Stefan P; Hauser, Anthony; Abel Zur Wiesch, Pia; Klein, Eili; Kouyos, Roger D  (2021). Identifying the drivers of multidrug-resistant Klebsiella pneumoniae at a European level. PLoS Computational Biology, 17:e1008446.

Tepekule, Burcu; Hauser, Anthony; Kachalov, Viacheslav N; Andresen, Sara; Scheier, Thomas; Schreiber, Peter W; Günthard, Huldrych F; Kouyos, Roger D  (2021). Assessing the potential impact of transmission during prolonged viral shedding on the effect of lockdown relaxation on COVID-19. PLoS Computational Biology, 17:e1008609.

Börold, Jacob. A Genome-Wide CRISPR/Cas Screen to Uncover Host Factors Regulating the Interferon Response and Virus Infection. 2021, University of Zurich, Medizinische Fakultät.

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Benet, Susana; Gálvez, Cristina; Drobniewski, Francis; et al; Günthard, Huldrych F  (2021). Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles. Journal of Extracellular Vesicles, 10(3):e12046.

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Wenk, Benjamin M; Mbunkah, Herbert A; Nsanwe, Ndi N; Mbu, Eyongetah T; Besong, Lydia M; Sama, Bella A; Orock, Emmanuel; Leemann, Christine; Metzner, Karin J  (2021). Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon. Journal of Antimicrobial Chemotherapy, 76(1):124-129.

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5. صف بإيجاز أعمال الدفاع البيولوجي التي أجريت بالمرفق، بما في ذلك نـوع (أنواع) الكائنات الدقيقة(9) و/أو التكسينات التي درست، وكذلك الدراسات الخارجية للإيروسولات البيولوجية.

The Institute of Medical Virology at the University of Zurich is the Regional Competence Center for the primary analysis of viral samples suspicious of a bioterror-related background. This represents an additional and not a continuous task of the viral diagnostics laboratory.

For further information please visit:
https://www.virology.uzh.ch/en.html

(9) ‫والبريونات‪.‬‬ ‫الفيروسات‬ ‫ذلك‬ ‫في‬ ‫بما‬