National Institute for Biological Standards and Control

2. Responsible public or private organization or company
The Medicines and Healthcare products Regulatory Agency, a Non-Departmental Public Body of the UK Department of Health & Social Care
3. Location and postal address
Blanche Lane, South Mimms, Potters Bar, Hertfordshire, EN6 3QG
4. Source(s) of financing of the reported activity, including indication if the activity is wholly or partly financed by the Ministry of Defence

UK Government (Department for Health and Social Care; Home Office)

5. Number of maximum containment units5 within the research centre and/or laboratory, with an indication of their respective size (SqM):
BL 4 , 59.00 SqM
BL 4 , 59.00 SqM
6. Scope and general description of activities, including type(s) of micro-organisms and/or toxins as appropriate

In general, the activities are related to development of assays and testing of reagents. During 2020 active projects involving the following organisms and/or toxinswere undertaken:

Highly pathogenic influenza virus – reagent development for highly pathogenic avian influenza (HPAI) viruses (H5Nx, H7N9) and associated research.

Bacillus anthracis toxins – made available for vaccine testing, reagent development, development of in vitro assays to detect anthrax toxin neutralising antibodies.

Botulinum toxins (serotypes A, B, E) - laboratory testing of therapeutic toxins; development of cell-based assays for clostridial toxins.


(4) For facilities with maximum containment units participating in the national biological defence research and development programme, please fill in name of facility and mark "Declared in accordance with Form A, part 2 (iii)".

(5) In accordance with the latest edition of the WHO Laboratory Biosafety Manual, or equivalent.