Laboratoires de Diagnostic de l’Institut de Microbiologie (Diagnostic Laboratories of the Institute of Microbiology)

2. Where is it located (include both address and geographical location)?

Laboratoires de Diagnostic de l’Institut de Microbiologie, Département de Pathologie et Médecine de Laboratoire, Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 48, CH-1011 Lausanne, Switzerland

N 46° 31' 30.57", E 6° 38' 29.15"

3. Floor area of laboratory areas by containment level
BL 3 , 77.00 SqM
Total laboratory floor area (SqM)

4. The organizational structure of each facility

(viii) Briefly describe the publication policy of the facility

Publication in open literature.

(ix) Provide a list of publicly-available papers and reports resulting from the work published during the previous 12 months. (To include authors, titles and full references)

Added Value of Xpert MTB/RIF Ultra for Diagnosis of Pulmonary Tuberculosis in a Low-Prevalence Setting. Opota O, Zakham F, Mazza-Stalder J, Nicod L, Greub G, Jaton K. J Clin Microbiol. 2019 Jan 30;57(2).

Prevalence of Anaplasma phagocytophilum and Coxiella burnetii in Ixodes ricinus ticks in Switzerland: an underestimated epidemiologic risk. Pilloux L, Baumgartner A, Jaton K, Lienhard R, Ackermann-Gäumann R, Beuret C, Greub G. New Microbes New Infect. 2018 Sep 6;27:22-26.

Comparison of analytical performances of the Roche Cobas 6800 CT/NG assay with the Abbott m2000 Real Time CT/NG assay for detecting Chlamydia trachomatis and Neisseria gonorrhoeae. Cherkaoui A, Renzi G, Mombelli M, Jaton K, Yerly S, Vuilleumier N, Schrenzel J. J Med Microbiol. 2019 Feb;68(2):197-200.

Role of bi-weekly serum galactomannan screening for the diagnosis of invasive aspergillosis in haematological cancer patients. Couchepin J, Brunel AS, Jaton K, Meylan P, Bochud PY, Lamoth F. Mycoses. 2018 Jun;61(6):350-354.

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study. Walker TM, Merker M, Knoblauch AM, Helbling P, Schoch OD, van der Werf MJ, Kranzer K, Fiebig L, Kröger S, Haas W, Hoffmann H, Indra A, Egli A, Cirillo DM, Robert J, Rogers TR, Groenheit R, Mengshoel AT, Mathys V, Haanperä M, Soolingen DV, Niemann S, Böttger EC, Keller PM; MDR-TB Cluster Consortium. Lancet Infect Dis. 2018. Apr;18(4):431-440.

5. Briefly describe the biological defence work carried out at the facility, including type(s) of micro-organisms(9) and/or toxins studied, as well as outdoor studies of biological aerosols.

The Diagnostic Laboratories of the Institute of Microbiology, which are part of the University Hospital of Lausanne, are the Regional Competence Center for the primary analysis of samples suspicious of a bioterror-related background. Due to its other diagnostic activities, it is able to cover the whole spectrum of microbiology.

Of note, in 2017, the Diagnostic Laboratories of the Institute of Microbiology obtained the necessary funds for an upgrade and expansion of its BSL3 laboratory. The construction started in February 2017 and will be finished in May 2019. During this period all these activities are carried out in the research BSL3 laboratory of the Institute according to the good laboratories practices recommended.

The new BSL3 laboratory will be the reference BSL3 laboratory of the hospital (CHUV) for the diagnosis and manipulation of BSL3 samples, strains, microorganisms that may be encountered in the daily work as well as environmental samples for the Regional Laboratory Network.

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(9) Including viruses and prions.