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Wehrwissenschaftliches Institut für Schutztechnologien – ABC-Schutz (Bundeswehr Research Institute for Protective Technologies and CBRN Protection)

2. Where is it located (include both address and geographical location)?

Humboldtstrasse 100, 29633 Munster/Oertze, Germany

53°00` N, 10°08` E

3. Floor area of laboratory areas by containment level
BL 3 , 6.00 SqM
containment (vehicle bound)
BL 3 , 360.00 SqM
stationary laboratories
BL 2 , 520.00 SqM
Total laboratory floor area (SqM)
886

4. The organizational structure of each facility

(viii) Briefly describe the publication policy of the facility

Results will be published in reports to the Federal Office of Equipment, IT and In-Service Support. They will also be presented in public scientific journals and in national and international scientific meetings and symposiums.

(ix) Provide a list of publicly-available papers and reports resulting from the work published during the previous 12 months. (To include authors, titles and full references)

Papers/Reports
1. Duda, S.; Sascha Hartig, S.; Hagner, K.; Meyer, L.; Wessling Intriago P.; Meyer, T.; Wessling H.
„Potential risks of a widespread use of 3D printing for the manufacturing of face masks during the severe acute respiratory syndrome coronavirus 2 pandemic“,
Journal of 3D Printing in Medicine, Vol. 4, No. 3 | Research Article, doi: 10.2217/3dp-2020-001
2. Goethe, R. et al.
„Complete Genome Sequence and Manual Reannotation of Mycobacterium avium subsp. paratuberculosis Strain DSM 44135“, Microbiology Resource Announcements,
9. 10.1128/MRA.00711-20, 2020

Oral Presentations
3. Fibinger, M.-P.-C.
„Das Biologische Labor des WIS, Schwerpunkte der Toxinologie“,
Universitäsklikum Eppendorf, Hamburg, 04.02.2020
4. Hesse, F., Wiemann, J., Dawert, T.
„Defence and security considerations for PPE arising from the COVID-19 crisis“,
Virtual meeting of NATO JCBRNCDG Physical Protection Panel, 1 to 2 December 2020
5. Klenner, J.
„NEXT GENERATION SEQUENCING (NGS) - BASED B-DETECTION“,
MAG & 115th NAAG, Special Session CBRND, NATO HQ, Brüssel, 05. - 07.02.2020
6. Reifer, E.
„Forschung zur Qualifikation mobiler Wasseraufbereitung“, Angewandte Forschung für Verteidigung und Sicherheit in Deutschland“,
Studiengesellschaft der DWT, Bonn, Germany, 03.03.2020
7. Wiemann, J.; Dawert, T.; Hagner, K.; Hesse, F.
„Design criteria of FFP-masks are as important as the selection of materials“,
Air Filtration Seminar 2020, Palas GmbH, Frankfurt am Main, Deutschland, 24.09.2020

Patents
8. Schache, C.; Köhne, S.
„Verlegbares Sicherheitscontainment mit einer Filterdichtsitzprüfeinrichtung“
Patent application

Committee work
9. Behrens-Gütschow, C., European Defence Agency – EDA Captech ESM04
10. Dawert, T.: NATO JCBRNCDG Physical Protection Panel, Revision STANREC 4727/AEP-73
11. Haverland, F., European Defence Agency – EDA Captech ESM04
12. Hülseweh, B., Mitglied des „Nationalen Labornetzwerkes für Diagnostik von Bioterroristischen Agenzien“ (NaLaDiBa), Forschungsvorhaben des BBK.
13. Hülseweh, B., Gutachterin für das zivile Sicherheisforschungsprogramm des BMBF
14. Köhne, S., Ausschuss für Biologische Arbeitsstoffe (ABAS), Vertreter BMVg
15. Köhne, S., ABAS UA 4 (Labortechnik)
16. Köhne, S., ABAS UA 2 – Arbeitskreis: Hochpathogene Viren
17. Köhne, S., ABAS UA 1 – Arbeitskreis: TRBA 130

Notes
N/A
Attachments
N/A
5. Briefly describe the biological defence work carried out at the facility, including type(s) of micro-organisms(9) and/or toxins studied, as well as outdoor studies of biological aerosols.

For these purposes, microbiological safety laboratories of biosafety levels BSL 1- 3 and biosafety
    S 1 laboratories for genetically engineered agents are operated, which allow development and research in all areas of B-protection and the investigation of suspect samples in case of CBRN scenarios.
    The mission is to close Bundeswehr capability gaps in B-defense. Development and optimization of the rapid identification/detection of biowarfare agents, development of the elemental basics for the generation and verification of protection factors and both outline and establishment of new and pioneering approaches in decontamination are the primary focus of the biological laboratories and B-detection.    
a.    Development of early-warning systems permitting non-specific identification of toxins, bacteria and viruses.
b.    Optimization of the properties of the available, previously generated detection molecules in their specificity, affinity and avidity for use in the immunological detection and identification systems, which inevitably must be suitable also for field-use. Using new technologies (e.g. development and identification of recombinant antibodies), the repertoire of antibodies and detection molecules for biological agents is constantly expanded.
c.    Optimization and automatization of immunological and molecular genetical identification methods.
d.    Development, testing and evaluation of equipment and procedures for sampling and rapid and accurate identification of toxins and pathogenic agents in samples from air, water, soil, vegetation (sensor-equipment, collectors, detection kits, automatisation).
e.    Sample concentration and preparation incl. inactivation for identification in different matrices.
f.    Efficient sample processing and risk mitigation method for both ensuring safe handling and preparation of the mixed CBRN samples for the following identification analysis of the CBRN agents. Aim is to develop a set of validated procedures for the separation and preparation of a potential mixture of CBRN agents into distinct C, B, RN aliquots for simultaneous, parallel and/or successive identification analyses, independent of sample matrix, without an impact on each CBRN compound and reducing the turn-around-time for analysis.
g.    Stability-tests for B-agents in different matrices.
h.    Risk assessment Improvised Explosive Devices (IED) plus B-agents.
i.    Development of procedures for disinfection and decontamination.
j.    B-Agents and toxin laboratory analysis of suspect samples.
k.    Toxin preparation and analytics.
l.    Participation in round-robin exercises.
m.    Nanotechnology for materials like clothes, paints, etc.
n.    Evaluation of B removal efficiency of water treatment equipment.
o.    Development and evaluation of mobile equipment for B monitoring of the water supply chain.

The current programme covers non-human/non-animal pathogen biosafety level 1 and pathogenic biosafety level 2 and 3 organisms as well as low-molecular weight toxins.
Outdoor studies were performed for biological aerosols detection and water-purification tests using biowarfare agent simulants like Bacillus atrophaeus, E. coli and phages.

(9) Including viruses and prions.