Institut für Medizinische Virologie (Institute of Medical Virology)

2. Ubicación (dirección y lugar geográfico)
Institut für Medizinische Virologie, Medizinische Fakultät, Universität Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

N 47° 23' 52.08", E 8° 33' 01.92"

3. Superficie de los laboratorios por nivel de contención
BL 3 , 25.00 m2
Of note, the Institute of Medical Virology holds a BSL4 license for diagnostic purposes only, as follows: “Inactivation or extraction of environmental samples or samples with potentially highly pathogenic viruses for diagnostic purposes”.
Superficie total de laboratorios (m(2))

4. Estructura orgánica de cada instalación

(viii) Describa brevemente la política de publicaciones de la instalación

Publication in open literature.

(ix) Enumere los trabajos e informes que se han hecho públicos resultantes de la labor desarrollada y publicados en los últimos doce meses (con indicación de autores, títulos y referencias completas)

Improved Diagnostics Help to Identify Clinical Features and Biomarkers That Predict Mycoplasma pneumoniae Community-acquired Pneumonia in Children. 
Meyer Sauteur PM, Krautter S, Ambroggio L, Seiler M, Paioni P, Relly C, Capaul R, Kellenberger C, Haas T, Gysin C, Bachmann LM, van Rossum AMC, Berger C.
Clin Infect Dis. 2020 Oct 23;71(7):1645-1654. doi: 10.1093/cid/ciz1059.
PMID: 31665253 Free PMC article. 

Symposium report: One Health meets sequencing. 
Egli A, Koch D, Danuser J, Hendriksen RS, Driesen S, Schmid DC, Neher R, Mäusezahl M, Seth-Smith HMB, Bloemberg G, Tschudin-Sutter S, Endimiani A, Perreten V, Greub G, Schrenzel J, Stephan R.
Microbes Infect. 2020 Jan-Feb;22(1):1-7. doi: 10.1016/j.micinf.2019.07.004. Epub 2019 Aug 8.
PMID: 31401354 No abstract available. 

EBV renders B cells susceptible to HIV-1 in humanized mice. 
McHugh D, Myburgh R, Caduff N, Spohn M, Kok YL, Keller CW, Murer A, Chatterjee B, Rühl J, Engelmann C, Chijioke O, Quast I, Shilaih M, Strouvelle VP, Neumann K, Menter T, Dirnhofer S, Lam JK, Hui KF, Bredl S, Schlaepfer E, Sorce S, Zbinden A, Capaul R, Lünemann JD, Aguzzi A, Chiang AK, Kempf W, Trkola A, Metzner KJ, Manz MG, Grundhoff A, Speck RF, Münz C.
Life Sci Alliance. 2020 Jun 23;3(8):e202000640. doi: 10.26508/lsa.202000640. Print 2020 Aug.
PMID: 32576602 Free PMC article. 

Absenteeism and presenteeism in healthcare workers due to respiratory illness. 
Kuster SP, Böni J, Kouyos RD, Huber M, Schmutz S, Shah C, Bischoff-Ferrari HA, Distler O, Battegay E, Giovanoli P, Guckenberger M, Kohler M, Müller R, Petry H, Ruschitzka F, McGeer A, Coleman BL, Sax H, Weber R, Trkola A.
Infect Control Hosp Epidemiol. 2020 Nov 26:1-6. doi: 10.1017/ice.2020.444. Online ahead of print.
PMID: 33239124 

Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART. 
Wan C, Bachmann N, Mitov V, Blanquart F, Céspedes SP, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Walti L, Calmy A, Vernazza P, Bernasconi E, Cavassini M, Metzner KJ, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.
Nat Commun. 2020 Nov 2;11(1):5542. doi: 10.1038/s41467-020-19198-7.
PMID: 33139735 Free PMC article. 

Evaluation of the RIDA®GENE RT-PCR assays for detection of sapovirus, astrovirus, adenovirus, and rotavirus in stool samples of adults in Switzerland. 
Redli PM, Wanzenried A, Huder JB, Berger C, Berlinger L, Capaul R, Böni J, Zbinden A.
Diagn Microbiol Infect Dis. 2020 Feb;96(2):114924. doi: 10.1016/j.diagmicrobio.2019.114924. Epub 2019 Nov 7.
PMID: 31757559 

Siblings with typhoid fever: An investigation of intrafamilial transmission, clonality, and antibiotic susceptibility. 
Meyer Sauteur PM, Stevens MJA, Paioni P, Wüthrich D, Egli A, Stephan R, Berger C, Bloemberg GV.
Travel Med Infect Dis. 2020 Mar-Apr;34:101498. doi: 10.1016/j.tmaid.2019.101498. Epub 2019 Sep 30.
PMID: 31580900 

Phylogenetic Cluster Analysis Identifies Virological and Behavioral Drivers of HIV Transmission in MSM. 
Bachmann N, Kusejko K, Nguyen H, Chaudron SE, Kadelka C, Turk T, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Ramette A, Vernazza P, Bernasconi E, Cavassini M, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.
Clin Infect Dis. 2020 Apr 17:ciaa411. doi: 10.1093/cid/ciaa411. Online ahead of print.
PMID: 32300807 

HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection. 
Carlisle LA, Turk T, Metzner KJ, Mbunkah HA, Shah C, Böni J, Huber M, Braun DL, Fehr J, Salazar-Vizcaya L, Rauch A, Yerly S, Nguyen A, Cavassini M, Stoeckle M, Vernazza P, Bernasconi E, Günthard HF, Kouyos RD.
Viruses. 2020 Oct 31;12(11):1241. doi: 10.3390/v12111241.
PMID: 33142675 Free PMC article. 

Mycobacterium helveticum sp. nov., a novel slowly growing mycobacterial species associated with granulomatous lesions in adult swine. 
Ghielmetti G, Rosato G, Trovato A, Friedel U, Kirchgaessner C, Perroulaz C, Pendl W, Schulthess B, Bloemberg GV, Keller PM, Stephan R, Tortoli E.
Int J Syst Evol Microbiol. 2020 Dec 23. doi: 10.1099/ijsem.0.004615. Online ahead of print.
PMID: 33355527 

Does respiratory co-infection facilitate dispersal of SARS-CoV-2? investigation of a super-spreading event in an open-space office. 
Weissberg D, Böni J, Rampini SK, Kufner V, Zaheri M, Schreiber PW, Abela IA, Huber M, Sax H, Wolfensberger A.
Antimicrob Resist Infect Control. 2020 Dec 2;9(1):191. doi: 10.1186/s13756-020-00861-z.
PMID: 33267855 Free PMC article. 

Attenuated immune control of Epstein-Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA-DR15. 
Zdimerova H, Murer A, Engelmann C, Raykova A, Deng Y, Gujer C, Rühl J, McHugh D, Caduff N, Naghavian R, Pezzino G, Capaul R, Zbinden A, Ferlazzo G, Lünemann JD, Martin R, Chatterjee B, Münz C.
Eur J Immunol. 2020 Sep 19. doi: 10.1002/eji.202048655. Online ahead of print.
PMID: 32949466 

Mycobacterial infections in wild boars (Sus scrofa) from Southern Switzerland: Diagnostic improvements, epidemiological situation and zoonotic potential. 
Ghielmetti G, Hilbe M, Friedel U, Menegatti C, Bacciarini L, Stephan R, Bloemberg G.
Transbound Emerg Dis. 2020 Jul 8. doi: 10.1111/tbed.13717. Online ahead of print.
PMID: 32640107 

A Novel Lineage of Ceftriaxone-resistant Salmonella Typhi From India That Is Closely Related to XDR S. Typhi Found in Pakistan. 
Sah R, Donovan S, Seth-Smith HMB, Bloemberg G, Wüthrich D, Stephan R, Kataria S, Kumar M, Singla S, Deswal V, Kaur A, Neumayr A, Hinic V, Egli A, Kuenzli E.
Clin Infect Dis. 2020 Aug 22;71(5):1327-1330. doi: 10.1093/cid/ciz1204.
PMID: 31872221 

Emergence of Resistance to Integrase Strand Transfer Inhibitors during Dolutegravir Containing Triple-Therapy in a Treatment-Experienced Patient with Pre-Existing M184V/I Mutation. 
Braun DL, Scheier T, Ledermann U, Flepp M, Metzner KJ, Böni J, Günthard HF.
Viruses. 2020 Nov 19;12(11):1330. doi: 10.3390/v12111330.
PMID: 33228206 Free PMC article. 

Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment. 
Thorball CW, Borghesi A, Bachmann N, Von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Roth V, Kok YL, Parbhoo S, Wieser M, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Schmid P, Bernasconi E, Cavassini M, Kouyos RD, Günthard HF, Metzner KJ, Fellay J; Swiss HIV Cohort Study.
J Acquir Immune Defic Syndr. 2020 Dec 1;85(4):517-524. doi: 10.1097/QAI.0000000000002473.
PMID: 33136754 

A treatment as prevention trial to eliminate hepatitis C among men who have sex with men living with HIV in the Swiss HIV Cohort Study. 
Braun DL, Hampel B, Ledergerber B, Grube C, Nguyen H, Künzler-Heule P, Shah C, Salazar-Vizcaya L, Conen A, Flepp M, Stöckle M, Béguelin C, Schmid P, Rougemont M, Delaloye J, Bernasconi E, Nicca D, Böni J, Rauch A, Kouyos RD, Günthard HF, Fehr JS.
Clin Infect Dis. 2020 Aug 6:ciaa1124. doi: 10.1093/cid/ciaa1124. Online ahead of print.
PMID: 32761122 

Differences in social and mental well-being of long-term survivors among people who inject drugs and other participants in the Swiss HIV Cohort Study: 1980-2018. 
Kusejko K, Marzel A, Nguyen H, Chaudron SE, Bachmann N, Weber R, Bruggmann P, Roth JA, Bernasconi E, Calmy A, Cavassini M, Bregenzer A, Böni J, Yerly S, Klimkait T, Perreau M, Walti LN, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.
Antivir Ther. 2020;25(1):43-54. doi: 10.3851/IMP3347.
PMID: 32235037 

Emergence of Drug Resistance in the Swiss HIV Cohort Study Under Potent Antiretroviral Therapy Is Observed in Socially Disadvantaged Patients. 
Abela IA, Scherrer AU, Böni J, Yerly S, Klimkait T, Perreau M, Hirsch HH, Furrer H, Calmy A, Schmid P, Cavassini M, Bernasconi E, Günthard HF; Swiss HIV Cohort Study.
Clin Infect Dis. 2020 Jan 2;70(2):297-303. doi: 10.1093/cid/ciz178.
PMID: 30843028 

The role of HIV asymptomatic status when starting ART on adherence and treatment outcomes and implications for test and treat: the Swiss HIV Cohort Study. 
Glass TR, Günthard H, Calmy A, Bernasconi E, Scherrer AU, Battegay M, Steffen A, Böni J, Yerly S, Klimkait T, Cavassini M, Furrer H; Swiss HIV Cohort Study.
Clin Infect Dis. 2020 Mar 11:ciaa239. doi: 10.1093/cid/ciaa239. Online ahead of print.
PMID: 32157270 

Listeriosis Caused by Persistence of Listeria monocytogenes Serotype 4b Sequence Type 6 in Cheese Production Environment. 
Nüesch-Inderbinen M, Bloemberg GV, Müller A, Stevens MJA, Cernela N, Kollöffel B, Stephan R.
Emerg Infect Dis. 2021 Jan;27(1):284-288. doi: 10.3201/eid2701.203266.
PMID: 33350924 Free PMC article. 

Archivos adjuntos
5. Describa brevemente la labor desarrollada por la instalación en materia de defensa biológica, con indicación de los tipos de microorganismos(9) y/o toxinas estudiados, así como las investigaciones al aire libre sobre los aerosoles biológicos

The Institute of Medical Virology at the University of Zurich is the Regional Competence Center for the primary analysis of viral samples suspicious of a bioterror-related background. This represents an additional and not a continuous task of the viral diagnostics laboratory.

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(9) Comprendidos virus y priones.