National Biological Defense Program

1. Indiquer les objectifs et le financement de chaque programme et résumer les principales activités de recherche-développement menées dans le cadre du programme, en particulier dans les secteurs suivants: prophylaxie, études de pouvoir pathogène et de virulence, techniques de diagnostic, aérobiologie, détection, traitement, toxinologie, protection physique, décontamination et autres recherches apparentées.

The objective is to establish national biological defense proficiency by developing and improving precise and accurate tests for the rapid diagnosis as well as for identification, including characterzation, of different biological agents and toxins using various methods. Spiez Laboratory is assigned to fulfill this task and to close any gaps to reach national biological defense excellence. To improve the national biological defense capabilities of Switzerland, Spiez Laboratory has funds available to run a dedicated program with the goal of added research and development mainly benefitting detection, diagnostic and identification techniques. A major part of the program is conducted under contract with national and international industries, academic institutions as well as domestic and foreign governmental agencies, as detailed in paragraph 5.

Spiez Laboratory is part of the Federal Office for Civil Protection FOCP within the Federal Department of Defence, Civil Protection and Sports DDPS of the Swiss Confederation. Spiez Laboratory is the Swiss center of expertise in protection against nuclear, biological and chemical (NBC) threats and hazards. Besides delivering its expertise to relevant stakeholders, the Biology Division of Spiez Laboratory is concerned with the identification of biological agents and toxins, as well as supports military biological protection units. The Biology Division has three main branches that are engaged in the fields of virology, bacteriology and toxinology, respectively.

Spiez Laboratory possesses a high containment facility that allows for the safe handling of biological agents of all risk groups. It is the only BSL4 high containment facility in Switzerland holding a license which is not limited to diagnostic purposes. It serves towards the comprehensive detection and identification of human pathogens. This enables Spiez Laboratory to act in the Regional Laboratory Network as both a Regional Competence Center and as a National Reference Center / National Reference Laboratory having all necessary capabilities and capacities at hand.

For additional information and more on the vision of a world without weapons of mass destruction please visit: https://www.labor-spiez.ch/enindex.htm

3. Certains éléments de ces programmes sont-ils exécutés sous contrat avec l’industrie, des institutions universitaires ou dans d’autres installations ne relevant pas de la défense?
oui
4. Dans l’affirmative, quelle est la proportion du total des fonds affectés à chaque programme dépensés dans ces installations, sous contrat ou autres?

10 %

5. Indiquer succinctement les objectifs et les secteurs de recherche de chaque programme exécuté sous contrat et dans d’autres installations au moyen des fonds indiqués au paragraphe 4.

All contracted research and development of the program is supervised by Spiez Laboratory. Please also refer to paragraph 1 above for additional details. The contractors part of the program in 2018 were as follows:

  • Eidgenössische Technische Hochschule Zürich – ETHZ
    Functional Genomics Center Zurich – FGCZ
    Winterthurerstrasse 190
    CH-8057 Zürich
    Switzerland
    Project title:  „Next Generation Sequencing“
  • Eidgenössische Technische Hochschule Zürich – ETHZ
    Center for Security Studies – CSS
    Haldeneggsteig 4, IFW
    CH-8092 Zürich
    Switzerland
    Project title:  „Analysis of trends in science and policy“
  • Medizinische Hochschule Hannover – MHH
    Institut für Toxikologie
    Carl-Neuberg-Strasse 1
    DE-30625 Hannover
    Germany
    Project title:  „Development of recombinant botulinum neurotoxins and assessing proteolytic stability and transepithelial transport”
  • Universität Bern – UniBE
    Institut für Infektionskrankheiten – IFIK
    Friedbühlstrasse 51
    CH-3010 Bern
    Switzerland
    Project title:  „Next Generation Sequencing“
  • Universität Bern – UniBE
    Interfaculty Bioinformatics Unit – IBU
    Baltzerstrasse 6
    CH-3012 Bern
    Switzerland
    Project title:  „Comparative genome-based analysis of Naegleria“
  • Université de Lausanne / Centre Hospitalier Universitaire Vaudois – Unil / CHUV
    Institut de microbiologie – IMUL
    Rue du Bugnon 48
    CH-1011 Lausanne
    Switzerland
    Project title:  „Assessment of tenacity of highly pathogenic viruses and evaluation of inactivation strategies for clinical samples and contaminated materials”
    Project title:  „Evaluation of an immune response against Ebolavirus after vaccination”
    Project title:  „Identification and evaluation of antiviral substances against Hantavirus infections”
  • Zürcher Hochschule für Angewandte Wissenschaften – ZHAW
    Institut für Chemie und Biologische Chemie – ICBC
    Einsiedlerstrasse 31
    CH-8820 Wädenswil
    Switzerland
    Project title:  „Detection of proteinaceous toxins“
6. Indiquer la structure (organisation) de chaque programme et ses relations hiérarchiques (sans omettre les installations individuelles participant au programme).

 

 

Schéma de téléchargement
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7. Fournir une déclaration conformément à la partie 2 iii) de la formule A pour chacune des installations, gouvernementales ou non, dont une partie importante des ressources sont consacrées à chaque programme national de recherche-développement en matière de défense biologique, sises sur le territoire de l’État auteur de la déclaration ou en un lieu quelconque placé sous sa juridiction ou son contrôle.

Please refer to Form A, part 2 (iii).

Pièces jointes
N/A