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    Institut für Medizinische Virologie (Institute of Medical Virology)

    2. 设施位于何处(包括地址和地理位置)？
    Institut für Medizinische Virologie, Medizinische Fakultät, Universität Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

    N 47° 23' 52.08", E 8° 33' 01.92"

    3. 实验室楼面面积，按封闭级别分列
    BL 3 , 25.00 平方米
    Of note, the Institute of Medical Virology holds a BSL4 license for diagnostic purposes only, as follows: “Inactivation or extraction of environmental samples or samples with potentially highly pathogenic viruses for diagnostic purposes”.
    实验室总楼面面积（平方米）: 
    25

    4. 每一设施的组织结构：

    人员
    (一) 人员总数: 
    3

    (二) 人员按军职和文职分列：

    军职: 
    0
    文职: 
    3

    (三) 人员按工作性质分列：

    科学家: 
    2
    工程师 : 
    0
    技术员: 
    1
    行政和后勤人员: 
    0
    (四) 科学家/工程人员学科一览表：

    Microbiology (virology).

    (五) 是否有合同人员在设施内工作？如果有，请说明大致人数：
    0
    资金
    (六) 列明设施从事的工作的资金来源，包括说明活动是否由国防部提供全部资金或部分资金？

    Cantons of Appenzell Ausserrhoden, Appenzell Innerrhoden, Glarus, Graubünden, Sankt Gallen, Schaffhausen, Thurgau, Zug, Zürich, and the Principality of Liechtenstein.

    Research
    Development
    Test & Evaluation
    Analysis / Diagnosis
    Education & Training
    Other activities

    0 %
    0 %
    10 %
    50 %
    10 %
    30 % (costs for maintenance and amortization)

    (七) 下列方案领域的供资水平：

    研究: 
    0 %
    发展 : 
    0 %
    测试和评估: 
    10 %
    (八) 简述设施关于发表论文和报告的政策：

    Publication in open literature.

    (九) 提供一份过去12个月内发表的因工作产生并可公开获得的论文和报告的清单。(请填明作者、标题和全部参考说明。)

    Improved Diagnostics Help to Identify Clinical Features and Biomarkers That Predict Mycoplasma pneumoniae Community-acquired Pneumonia in Children. 
    Meyer Sauteur PM, Krautter S, Ambroggio L, Seiler M, Paioni P, Relly C, Capaul R, Kellenberger C, Haas T, Gysin C, Bachmann LM, van Rossum AMC, Berger C.
    Clin Infect Dis. 2020 Oct 23;71(7):1645-1654. doi: 10.1093/cid/ciz1059.
    PMID: 31665253 Free PMC article. 

    Symposium report: One Health meets sequencing. 
    Egli A, Koch D, Danuser J, Hendriksen RS, Driesen S, Schmid DC, Neher R, Mäusezahl M, Seth-Smith HMB, Bloemberg G, Tschudin-Sutter S, Endimiani A, Perreten V, Greub G, Schrenzel J, Stephan R.
    Microbes Infect. 2020 Jan-Feb;22(1):1-7. doi: 10.1016/j.micinf.2019.07.004. Epub 2019 Aug 8.
    PMID: 31401354 No abstract available. 

    EBV renders B cells susceptible to HIV-1 in humanized mice. 
    McHugh D, Myburgh R, Caduff N, Spohn M, Kok YL, Keller CW, Murer A, Chatterjee B, Rühl J, Engelmann C, Chijioke O, Quast I, Shilaih M, Strouvelle VP, Neumann K, Menter T, Dirnhofer S, Lam JK, Hui KF, Bredl S, Schlaepfer E, Sorce S, Zbinden A, Capaul R, Lünemann JD, Aguzzi A, Chiang AK, Kempf W, Trkola A, Metzner KJ, Manz MG, Grundhoff A, Speck RF, Münz C.
    Life Sci Alliance. 2020 Jun 23;3(8):e202000640. doi: 10.26508/lsa.202000640. Print 2020 Aug.
    PMID: 32576602 Free PMC article. 

    Absenteeism and presenteeism in healthcare workers due to respiratory illness. 
    Kuster SP, Böni J, Kouyos RD, Huber M, Schmutz S, Shah C, Bischoff-Ferrari HA, Distler O, Battegay E, Giovanoli P, Guckenberger M, Kohler M, Müller R, Petry H, Ruschitzka F, McGeer A, Coleman BL, Sax H, Weber R, Trkola A.
    Infect Control Hosp Epidemiol. 2020 Nov 26:1-6. doi: 10.1017/ice.2020.444. Online ahead of print.
    PMID: 33239124 

    Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART. 
    Wan C, Bachmann N, Mitov V, Blanquart F, Céspedes SP, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Walti L, Calmy A, Vernazza P, Bernasconi E, Cavassini M, Metzner KJ, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.
    Nat Commun. 2020 Nov 2;11(1):5542. doi: 10.1038/s41467-020-19198-7.
    PMID: 33139735 Free PMC article. 

    Evaluation of the RIDA®GENE RT-PCR assays for detection of sapovirus, astrovirus, adenovirus, and rotavirus in stool samples of adults in Switzerland. 
    Redli PM, Wanzenried A, Huder JB, Berger C, Berlinger L, Capaul R, Böni J, Zbinden A.
    Diagn Microbiol Infect Dis. 2020 Feb;96(2):114924. doi: 10.1016/j.diagmicrobio.2019.114924. Epub 2019 Nov 7.
    PMID: 31757559 

    Siblings with typhoid fever: An investigation of intrafamilial transmission, clonality, and antibiotic susceptibility. 
    Meyer Sauteur PM, Stevens MJA, Paioni P, Wüthrich D, Egli A, Stephan R, Berger C, Bloemberg GV.
    Travel Med Infect Dis. 2020 Mar-Apr;34:101498. doi: 10.1016/j.tmaid.2019.101498. Epub 2019 Sep 30.
    PMID: 31580900 

    Phylogenetic Cluster Analysis Identifies Virological and Behavioral Drivers of HIV Transmission in MSM. 
    Bachmann N, Kusejko K, Nguyen H, Chaudron SE, Kadelka C, Turk T, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Ramette A, Vernazza P, Bernasconi E, Cavassini M, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.
    Clin Infect Dis. 2020 Apr 17:ciaa411. doi: 10.1093/cid/ciaa411. Online ahead of print.
    PMID: 32300807 

    HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection. 
    Carlisle LA, Turk T, Metzner KJ, Mbunkah HA, Shah C, Böni J, Huber M, Braun DL, Fehr J, Salazar-Vizcaya L, Rauch A, Yerly S, Nguyen A, Cavassini M, Stoeckle M, Vernazza P, Bernasconi E, Günthard HF, Kouyos RD.
    Viruses. 2020 Oct 31;12(11):1241. doi: 10.3390/v12111241.
    PMID: 33142675 Free PMC article. 

    Mycobacterium helveticum sp. nov., a novel slowly growing mycobacterial species associated with granulomatous lesions in adult swine. 
    Ghielmetti G, Rosato G, Trovato A, Friedel U, Kirchgaessner C, Perroulaz C, Pendl W, Schulthess B, Bloemberg GV, Keller PM, Stephan R, Tortoli E.
    Int J Syst Evol Microbiol. 2020 Dec 23. doi: 10.1099/ijsem.0.004615. Online ahead of print.
    PMID: 33355527 

    Does respiratory co-infection facilitate dispersal of SARS-CoV-2? investigation of a super-spreading event in an open-space office. 
    Weissberg D, Böni J, Rampini SK, Kufner V, Zaheri M, Schreiber PW, Abela IA, Huber M, Sax H, Wolfensberger A.
    Antimicrob Resist Infect Control. 2020 Dec 2;9(1):191. doi: 10.1186/s13756-020-00861-z.
    PMID: 33267855 Free PMC article. 

    Attenuated immune control of Epstein-Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA-DR15. 
    Zdimerova H, Murer A, Engelmann C, Raykova A, Deng Y, Gujer C, Rühl J, McHugh D, Caduff N, Naghavian R, Pezzino G, Capaul R, Zbinden A, Ferlazzo G, Lünemann JD, Martin R, Chatterjee B, Münz C.
    Eur J Immunol. 2020 Sep 19. doi: 10.1002/eji.202048655. Online ahead of print.
    PMID: 32949466 

    Mycobacterial infections in wild boars (Sus scrofa) from Southern Switzerland: Diagnostic improvements, epidemiological situation and zoonotic potential. 
    Ghielmetti G, Hilbe M, Friedel U, Menegatti C, Bacciarini L, Stephan R, Bloemberg G.
    Transbound Emerg Dis. 2020 Jul 8. doi: 10.1111/tbed.13717. Online ahead of print.
    PMID: 32640107 

    A Novel Lineage of Ceftriaxone-resistant Salmonella Typhi From India That Is Closely Related to XDR S. Typhi Found in Pakistan. 
    Sah R, Donovan S, Seth-Smith HMB, Bloemberg G, Wüthrich D, Stephan R, Kataria S, Kumar M, Singla S, Deswal V, Kaur A, Neumayr A, Hinic V, Egli A, Kuenzli E.
    Clin Infect Dis. 2020 Aug 22;71(5):1327-1330. doi: 10.1093/cid/ciz1204.
    PMID: 31872221 

    Emergence of Resistance to Integrase Strand Transfer Inhibitors during Dolutegravir Containing Triple-Therapy in a Treatment-Experienced Patient with Pre-Existing M184V/I Mutation. 
    Braun DL, Scheier T, Ledermann U, Flepp M, Metzner KJ, Böni J, Günthard HF.
    Viruses. 2020 Nov 19;12(11):1330. doi: 10.3390/v12111330.
    PMID: 33228206 Free PMC article. 

    Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment. 
    Thorball CW, Borghesi A, Bachmann N, Von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Roth V, Kok YL, Parbhoo S, Wieser M, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Schmid P, Bernasconi E, Cavassini M, Kouyos RD, Günthard HF, Metzner KJ, Fellay J; Swiss HIV Cohort Study.
    J Acquir Immune Defic Syndr. 2020 Dec 1;85(4):517-524. doi: 10.1097/QAI.0000000000002473.
    PMID: 33136754 

    A treatment as prevention trial to eliminate hepatitis C among men who have sex with men living with HIV in the Swiss HIV Cohort Study. 
    Braun DL, Hampel B, Ledergerber B, Grube C, Nguyen H, Künzler-Heule P, Shah C, Salazar-Vizcaya L, Conen A, Flepp M, Stöckle M, Béguelin C, Schmid P, Rougemont M, Delaloye J, Bernasconi E, Nicca D, Böni J, Rauch A, Kouyos RD, Günthard HF, Fehr JS.
    Clin Infect Dis. 2020 Aug 6:ciaa1124. doi: 10.1093/cid/ciaa1124. Online ahead of print.
    PMID: 32761122 

    Differences in social and mental well-being of long-term survivors among people who inject drugs and other participants in the Swiss HIV Cohort Study: 1980-2018. 
    Kusejko K, Marzel A, Nguyen H, Chaudron SE, Bachmann N, Weber R, Bruggmann P, Roth JA, Bernasconi E, Calmy A, Cavassini M, Bregenzer A, Böni J, Yerly S, Klimkait T, Perreau M, Walti LN, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.
    Antivir Ther. 2020;25(1):43-54. doi: 10.3851/IMP3347.
    PMID: 32235037 

    Emergence of Drug Resistance in the Swiss HIV Cohort Study Under Potent Antiretroviral Therapy Is Observed in Socially Disadvantaged Patients. 
    Abela IA, Scherrer AU, Böni J, Yerly S, Klimkait T, Perreau M, Hirsch HH, Furrer H, Calmy A, Schmid P, Cavassini M, Bernasconi E, Günthard HF; Swiss HIV Cohort Study.
    Clin Infect Dis. 2020 Jan 2;70(2):297-303. doi: 10.1093/cid/ciz178.
    PMID: 30843028 

    The role of HIV asymptomatic status when starting ART on adherence and treatment outcomes and implications for test and treat: the Swiss HIV Cohort Study. 
    Glass TR, Günthard H, Calmy A, Bernasconi E, Scherrer AU, Battegay M, Steffen A, Böni J, Yerly S, Klimkait T, Cavassini M, Furrer H; Swiss HIV Cohort Study.
    Clin Infect Dis. 2020 Mar 11:ciaa239. doi: 10.1093/cid/ciaa239. Online ahead of print.
    PMID: 32157270 

    Listeriosis Caused by Persistence of Listeria monocytogenes Serotype 4b Sequence Type 6 in Cheese Production Environment. 
    Nüesch-Inderbinen M, Bloemberg GV, Müller A, Stevens MJA, Cernela N, Kollöffel B, Stephan R.
    Emerg Infect Dis. 2021 Jan;27(1):284-288. doi: 10.3201/eid2701.203266.
    PMID: 33350924 Free PMC article. 
     

    笔记
    N/A
    附件
    N/A
    5. 简述设施内进行的生物战防御工作，包括研究的微生物1 和/或毒素的类型以及生物气雾剂户外研究。

    The Institute of Medical Virology at the University of Zurich is the Regional Competence Center for the primary analysis of viral samples suspicious of a bioterror-related background. This represents an additional and not a continuous task of the viral diagnostics laboratory.

    For further information please visit:
    https://www.virology.uzh.ch/index_en.html

    (9) 包括病毒和朊粒。

    报告索引