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National Biological Defense Program

1. 说明方案的目标和供资情况,概述方案中进行的主要研究与发展活动。述及的领域应包括:预防、致病性和毒性研究、诊断技术研究、大气生物学研究、检测研究、治疗研究、毒理学研究、实际防护研究、消除污染研究和其他有关研究。

The objective is to establish national biological defense proficiency by developing and improving precise and accurate tests for the rapid diagnosis as well as for identification and characterzation, of different biological agents and toxins using various methods. Spiez Laboratory is assigned to fulfill this task and to close any gaps to reach national biological defense excellence. To improve the national biological defense capabilities of Switzerland, Spiez Laboratory has funds available to run a dedicated program with the goal of added research and development mainly benefitting detection, diagnostic and identification techniques. Part of the program is conducted under contract with national and international industries, academic institutions as well as domestic and foreign governmental agencies, as detailed in paragraph 5.

Spiez Laboratory is part of the Federal Office for Civil Protection FOCP within the Federal Department of Defence, Civil Protection and Sports DDPS of the Swiss Confederation. Spiez Laboratory is the Swiss center of expertise in protection against nuclear, biological and chemical (NBC) threats and hazards. Besides delivering its expertise to relevant stakeholders, the Biology Division of Spiez Laboratory is concerned with the identification of biological agents and toxins, as well as supports military biological protection units. The Biology Division has expertise in the fields of virology, bacteriology and toxinology, as well as biosafety and biosecurity.

Spiez Laboratory possesses a high containment facility that allows for the safe handling of biological agents of all risk groups. It is the only BSL4 high containment facility in Switzerland holding a license which is not limited to diagnostic purposes. It serves towards the comprehensive detection and identification of human pathogens. This enables Spiez Laboratory to act in the Regional Laboratory Network as both a Regional Competence Center and as a National Reference Center / National Reference Laboratory having all necessary capabilities and capacities at hand.

For additional information and more on the vision of a world without weapons of mass destruction please visit:
https://www.labor-spiez.ch/enindex.htm

3. 这些方案的各部分是否以合同方式交由工业界、学术机构或其他不属于国防部门的设施进行?
4. 如果答复为“是”,为每一方案提供的资金总额中拨出多大比例给上述承包设施或其他设施?

10 %

5. 概述由承包者和其他设施以第4段所指资金执行的每一方案的目标和研究领域。

All contracted research and development of the program is supervised by Spiez Laboratory. Please also refer to paragraph 1 above for additional details. The contractors part of the program in 2020 were as follows:

  • Eidgenössische Technische Hochschule Zürich – ETHZ
    Functional Genomics Center Zurich – FGCZ
    Winterthurerstrasse 190
    CH-8057 Zürich
    Switzerland
    Project title:  „Next Generation Sequencing“

 

  • Eidgenössische Technische Hochschule Zürich – ETHZ
    Center for Security Studies – CSS
    Haldeneggsteig 4, IFW
    CH-8092 Zürich
    Switzerland
    Project title:  „Analysis of trends in science and policy“

 

  • Robert Koch-Institut – RKI
    Zentrum für Biologische Toxine – ZBS3
    Nordufer 20
    DE-13353 Berlin
    Germany
    Project title: „Staphylococcus enterotoxins analysis in food“

 

  • Scuola Universitaria Professionale della Svizzera Italiana – SUPSI
    Laboratorio Microbiologia applicata
    Via Mirasole 22a
    CH-6500 Bellinzona
    Switzerland
    Project title: “Vector Surveillance”
    Project title: „Development of mass spectrometric sequencing procedures to identify biomarkers“

 

  • Swiss Tropical and Public Health Institute – SwissTPH
    Socinstrasse 57
    CH-4051 Basel
    Switzerland
    Project title: „Next Generation Sequencing”

 

  • Universität Bern – UniBE
    Department for BioMedical Research – DBMR
    Sahli-Haus 2
    CH-3010 Bern
    Switzerland
    Project title:  „Assessment of tenacity of highly pathogenic viruses, antivirals and inactivation strategies as well as evaluation of clinical samples”

 

  • Universität Bern – UniBE
    Interfaculty Bioinformatics Unit – IBU
    Baltzerstrasse 6
    CH-3012 Bern
    Switzerland
    Project title:  „Functional characterization of Francisella tularensis holarctica genotypes by means of proteomics“
    Project title:  „Implementation of proteogenomic procedures to identify and characterize risk group 3 bacteria“

 

  • Université de Lausanne / Centre Hospitalier Universitaire Vaudois – Unil / CHUV
    Institut de microbiologie – IMUL
    Rue du Bugnon 48
    CH-1011 Lausanne
    Switzerland
    Project title:  „Novel therapeutic strategies against highly pathogenic viruses”
    Project title:  „Identification and evaluation of antiviral substances against Hantavirus infections”

 

  • Zürcher Hochschule für Angewandte Wissenschaften – ZHAW
    Institut für Chemie und Biologische Chemie – ICBC
    Einsiedlerstrasse 31
    CH-8820 Wädenswil
    Switzerland
    Project title:  „Detection of proteinaceous toxins“
6. 图示每一方案的组织结构和报告关系(包括参与方案的各设施)。

 

 

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7. 根据表格A第2(三)部分宣布报告国领土内或其管辖或控制下的任何地方把很大一部分资源专用于执行每一国家生物战防御研究与发展方案的每一政府设施和非政府设施。

Please refer to Form A, part 2 (iii).

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