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    Institut für Medizinische Virologie (Institute of Medical Virology)

    2. 设施位于何处(包括地址和地理位置)？
    Institut für Medizinische Virologie, Medizinische Fakultät, Universität Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

    N 47° 23' 52.08", E 8° 33' 01.92"

    3. 实验室楼面面积，按封闭级别分列
    BL 3 , 25.00 平方米
    Of note, the Institute of Medical Virology holds a BSL4 license for diagnostic purposes only, as follows: “Inactivation of environmental samples and of potentially highly pathogenic viruses for diagnostic purposes within the framework of the Regional Laboratory Network”.
    实验室总楼面面积（平方米）: 
    25

    4. 每一设施的组织结构：

    人员
    (一) 人员总数: 
    2

    (二) 人员按军职和文职分列：

    军职: 
    0
    文职: 
    2

    (三) 人员按工作性质分列：

    科学家: 
    1
    工程师 : 
    0
    技术员: 
    1
    行政和后勤人员: 
    0
    (四) 科学家/工程人员学科一览表：

    Microbiology (virology).

    (五) 是否有合同人员在设施内工作？如果有，请说明大致人数：
    0
    资金
    (六) 列明设施从事的工作的资金来源，包括说明活动是否由国防部提供全部资金或部分资金？

    Cantons of Appenzell Ausserrhoden, Appenzell Innerrhoden, Glarus, Graubünden, Sankt Gallen, Schaffhausen, Thurgau, Zug, Zürich, and the Principality of Liechtenstein.

    Research
    Development
    Test & Evaluation
    Analysis / Diagnosis
    Education & Training
    Other activities

    0 %
    0 %
    10 %
    50 %
    10 %
    30 % (costs for maintenance and amortization)

    (七) 下列方案领域的供资水平：

    研究: 
    0 %
    发展 : 
    0 %
    测试和评估: 
    10 %
    (八) 简述设施关于发表论文和报告的政策：

    Publication in open literature.

    (九) 提供一份过去12个月内发表的因工作产生并可公开获得的论文和报告的清单。(请填明作者、标题和全部参考说明。)

    Metagenomic virome sequencing in living donor-recipient kidney transplant pairs revealed JC Polyomavirus transmission. Schreiber PW, Kufner V, Hübel K, Schmutz S, Zagordi O, Kaur A, Bayard C, Greiner M, Zbinden A, Capaul R, Böni J, Hirsch HH, Mueller TF, Mueller NJ, Trkola A, Huber M. Clin Infect Dis. 2018 Dec 2. doi: 10.1093/cid/ciy1018.

    Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study. Kusejko K, Kadelka C, Marzel A, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD; Swiss HIV Cohort Study. Virus Evol. 2018 Sep 18;4(2):vey024. doi: 10.1093/ve/vey024. eCollection 2018 Jul. Review.

    Tracing HIV-1 strains that imprint broadly neutralizing antibody responses. Kouyos RD, Rusert P, Kadelka C, Huber M, Marzel A, Ebner H, Schanz M, Liechti T, Friedrich N, Braun DL, Scherrer AU, Weber J, Uhr T, Baumann NS, Leemann C, Kuster H, Chave JP, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Metzner KJ, Günthard HF, Trkola A; Swiss HIV Cohort Study. Nature. 2018 Sep;561(7723):406-410. doi: 10.1038/s41586-018-0517-0. Epub 2018 Sep 10.

    Quantifying the drivers of HIV transmission and prevention in men who have sex with men: a population model-based analysis in Switzerland. Kusejko K, Marzel A, Hampel B, Bachmann N, Nguyen H, Fehr J, Braun DL, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD; Swiss HIV Cohort Study. HIV Med. 2018 Nov;19(10):688-697. doi: 10.1111/hiv.12660. Epub 2018 Jul 26.

    The Cumulative Impact of Harm Reduction on the Swiss HIV Epidemic: Cohort Study, Mathematical Model, and Phylogenetic Analysis. Marzel A, Kusejko K, Weber R, Bruggmann P, Rauch A, Roth JA, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Günthard HF, Kouyos RD; Swiss HIV Cohort Study . Open Forum Infect Dis. 2018 May 19;5(5):ofy078. doi: 10.1093/ofid/ofy078. eCollection 2018 May.

    Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity. Kadelka C, Liechti T, Ebner H, Schanz M, Rusert P, Friedrich N, Stiegeler E, Braun DL, Huber M, Scherrer AU, Weber J, Uhr T, Kuster H, Misselwitz B, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Kouyos RD, Günthard HF, Trkola A; Swiss HIV Cohort Study. J Exp Med. 2018 Jun 4;215(6):1589-1608. doi: 10.1084/jem.20180246. Epub 2018 May 24.

    CD4 cell count response to first-line combination ART in HIV-2+ patients compared with HIV-1+ patients: a multinational, multicohort European study. Wittkop L, Arsandaux J, Trevino A, Schim van der Loeff M, Anderson J, van Sighem A, Böni J, Brun-Vezinet F, Soriano V, Boufassa F, Brockmeyer N, Calmy A, Dabis F, Jarrin I, Dorrucci M, Duque V, Fätkenheuer G, Zangerle R, Ferrer E, Porter K, Judd A, Sipsas NV, Lambotte O, Shepherd L, Leport C, Morrison C, Mussini C, Obel N, Ruelle J, Schwarze-Zander C, Sonnerborg A, Teira R, Torti C, Valadas E, Colin C, Friis-Møller N, Costagliola D, Thiebaut R, Chene G, Matheron S; COHERE in EuroCoord and ACHIeV2e Study Group. J Antimicrob Chemother. 2017 Oct 1;72(10):2869-2878. doi: 10.1093/jac/dkx210.

    Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity. Bertels F, Marzel A, Leventhal G, Mitov V, Fellay J, Günthard HF, Böni J, Yerly S, Klimkait T, Aubert V, Battegay M, Rauch A, Cavassini M, Calmy A, Bernasconi E, Schmid P, Scherrer AU, Müller V, Bonhoeffer S, Kouyos R, Regoes RR; Swiss HIV Cohort Study. Mol Biol Evol. 2018 Jan 1;35(1):27-37. doi: 10.1093/molbev/msx246.

    笔记
    N/A
    附件
    N/A
    5. 简述设施内进行的生物战防御工作，包括研究的微生物1 和/或毒素的类型以及生物气雾剂户外研究。

    The Institute of Medical Virology at the University of Zurich is the Regional Competence Center for the primary analysis of viral samples suspicious of a bioterror-related background. This represents an additional and not a continuous task of the viral diagnostics laboratory.

    For further information please visit:
    https://www.virology.uzh.ch/index_en.html

    (9) 包括病毒和朊粒。

    报告索引